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Without adequate glutathione reserves, acetaldehyde accumulates in hepatocytes and crosses the blood-brain barrier, where it disrupts neurotransmitter synthesis and causes the cognitive symptoms of hangover

The most frequently reported issues include: Nausea and occasional vomiting Diarrhea or constipation Abdominal pain and decreased appetite Rare But Serious Risks Like all GLP-1s, Rybelsus carries a black-box warning for a rare risk of thyroid C-cell tumors, based on rodent studies

This isnt about calling that advice wrong

Most people will experience mild symptoms that resolve as the body adjusts to the medication