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Frequently Asked Questions Why might appetite suppression persist even as semaglutide blood levels fall

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Researchers have also shown that semaglutide impacts the reward and punishment systems in the brains of mice, particularly in the nucleus accumbens region, which is part of the limbic system.433 It is believed that alcohol activates the brains reward and punishment system, triggering the release of dopamine, a neurotransmitter associated with pleasure and reward, both in humans and animals

Its also sold in combination with a drug called topiramate in a medication called Qsymia