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These medications, which function by slowing gastric emptying, can lead to severe, chronic digestive issues, including persistent nausea, vomiting, abdominal distention, and the need for intensive medical interventions like IV therapy or feeding tubes

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In low-calorie soft drinks, NielsenIQ saw a shift from diet to zero sugar sodawith ounce consumption down 12% in diet but up 19% in zero sugar 90 days after starting the medication

This mechanism, independent of mitochondrial mass changes, optimizes complex I/II activity and regulates carnitine acylcarnitine translocase to enhance substrate switching