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Pancreatitis risk has been studied extensively

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doi:10.1007/s00125-010-1937-z Lauffer L, Grieco A, Iakoubov R, Brubaker PL (2009) Metformin activates the AMPK pathway and improves survival of murine and human L-cells but does not directly increase GLP-1 secretion

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Insulin resistance

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aerobic exercise on antioxidant activity and cognitive function in individuals with Parkinsons disease

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