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Researchers must perform additional clinical studies to confirm these effects and determine how to use them in therapy

Approval processes, pricing, and actual effectiveness influence the speed at which it reaches the market

While SGLT2-i and GLP-1RA may offer additive or synergistic benefits in reducing BP and cardiovascular risk, current guidelines do not support their role as first-line antihypertensive agents or early adjunctive therapies over established agents such as thiazide diuretics, renin-angiotensin system (RAS) inhibitors, or calcium channel blockers (CCBs)

the potential for better health to positively improve productivity, absenteeism and presenteeism