Dundar HA, Kiray M, Kir M, Kolatan E, Bagriyanik A, Altun Z, Aktas S, Ellidokuz H, Yilmaz O, Mutafoglu K, Olgun N (2016) Protective effect of acetyl-L-carnitine against doxorubicin-induced cardiotoxicity in Wistar albino rats
Finally, selective regulation within the sirtuin family is essential, as overactivation of SIRT1 could disrupt the functional balance of related sirtuins, necessitating careful control of activation intensity and tissue- or subcellular-specific delivery
The pH is 5.7 (4.5 to 7.0)
In sensitivity analysis, we also included an isoform of l-carnitine, acetyl-carnitine, proxied by three genetic variants reaching genome-wide significance from the same GWAS as l-carnitine [20]