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This research was a phase 3 clinical trial involving people with metabolic dysfunction-associated steatohepatitis (MASH)

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The muscle loss concern, while often overstated, remains clinically relevant for older or frail patientsresearch shows GLP-1-induced weight loss does not cause disproportionate muscle loss in middle-aged adults, but resistance training and adequate protein intake remain essential recommendations

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[14] Because ALA can lower blood sugar, some patients (especially those with diabetes) may experience signs of mild hypoglycemia, such as dizziness, sweating, or lightheadedness, during ALA therapy if their blood sugar drops too low

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This means insulin is released only when blood glucose levels are elevated, reducing the risk of hypoglycaemia compared with some other diabetes medications

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