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Subsequently, for each semaglutide backbone sequence, Modeller [44] was used to generate at least 6000 homology structural models of GLP-1R-semaglutide analogue with PDB entry 4ZGM [29, 52] as template

The factors included in the additive regression were the same as those included in the multivariable linear regression model, and the number of imputations was set to 5