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According to FDA labeling and American Diabetes Association guidelines, GLP-1 receptor agonists are indicated for type 2 diabetes (as an adjunct to diet and exercise) and for chronic weight management in adults with BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity
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This modification typically occurs under oxidative stress, when the ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG) decreases (Suvorava et al., 2017
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