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The largest Phase 3 trials involved thousands of participants, yet joint pain was not flagged as a primary safety concern

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Hypothyroidism is not listed as a contraindication in the Wegovy prescribing information

There is no reason to combine these medications as they target the same receptor so you would just be engaging in overkill with no additional benefits However, there are times when you can add additional or stack peptides such as CJC 1295/Ipamorelin, AOD 9604, or MOTS-C, although these would need pre-approval from one of our medical providers How do I avoid GI (gastrointestinal) upset