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Current diagnostics rely on medical history, physical examination, and clinical observations, which often require many trips to the doctor and can be exhausting for a patient (56)

The reaction was started by adding 3 U of GR and was monitored by measuring the change in absorbance at 412 nm for 1 min

Disruption of this microbial ecosystem, which is known as gut dysbiosis, is nowadays thought to contribute to the development of many intestinal (IBS, IBD, and colorectal cancer) and extraintestinal (obesity, type 2 diabetes, and CNS-related disorders) disorders [71]

Criticisms have been raised about the secondary eye outcomes in the SUSTAIN-6 and PIONEER-6 trials