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Semaglutide GLP-1 vs Tirzepatide for Weight Loss in Adults with Overweight or Obesity Q&A Semaglutide GLP-1 and tirzepatide are advanced weight loss medications for adults with obesity or overweight

Versus other triple/multi-agonists in development : survodutide (GLP-1/GCGR Boehringer Ingelheim), mazdutide (GLP-1/GCGR Eli Lilly), orforglipron (oral non-peptide GLP-1 Eli Lilly), HRS9531 (GLP-1/GIP Hengrui): each represents a distinct signaling architecture

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A few patients were forced to discontinue treatment if the symptoms persisted, and this was unusual