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In a Phase Ib study for patients with Type 2 Diabetes (T2D), although no significant improvement in HbA1c levels was observed, pemvidutide still achieved a weight reduction of 8.5% at the end of a 12-week course compared to placebo
While typically an adaptive response, excessive hypertrophy from enzyme induction of hypertrophy can lead to hepatocellular degeneration and necrosis
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[DOI] [PubMed] [Google Scholar] 147.De Farias C.C., Maes M., Bonifcio K.L., Bortolasci C.C., Nogueira A.S., Brinholi F.F., Matsumoto A.K., do Nascimento M.A., Melo L.B., Nixdorf S.L., et al
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