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GLP-1RAs deliver high-intensity, pharmacologically sustained signals that reliably induce weight loss, whereas postbiotics provide low-intensity but continuous modulation of gut-derived signaling that shapes metabolic context (Table 1 and conceptually illustrated in Figure 1
This activation increases feelings of fullness at smaller meal portions, reduces cravings for high-calorie foods, and slows gastric emptying so nutrients stay in the stomach longer
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