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TUG1miR-148bIGF-2 The lncRNA TUG1 (taurine up-regulated gene 1) is believed to act in cardiovascular disease by enhancing atherosclerosis in part through an increase in vascular smooth muscle cell (VSMC) proliferation and survival [78]

Similar to the mechanism GSTs use for catalyzation of redox reactions, the mechanism for detoxification first involves the binding of two substrates to the enzyme

Intriguingly, and as mentioned above, PDAC cells are dependent on GOT1 and the malate-aspartate shuttle

A novel functional polymorphism of GSTM3 reduces clear cell renal cell carcinoma risk through enhancing its expression by interfering miR-556 binding