Clinical trials have shown a reduction in HbA 1c (0.30.4% [34 mmol/mol]) and modest (~1 kg) weight loss [251,252,253,254]
& Barco, A
This article summarizes the significant advances in understanding the role of miRNAs in the pathophysiology of type 2 diabetes and their potential application as biomarkers

Methodology The databases of Web of Science, PubMed, and Google Scholar were searched for this narrative review by the following keywords: hypertension, blood pressure, hypotensive, antihypertensive, hypertensive, diuretic, diabetes, hyperglycemia, insulin, hypoglycemic, antihyperglycemic, antidiabetic, blood glucose, HbA1c, dyslipidemia, hyperlipidemia, high cholesterol, high triglyceride, hypercholesterolemia, hypertriglyceridemia, hypoglycemic, hypolipidemic, hypoglycaemic, hypolipidaemic, lipid-lowering, atherogenic, atherosclerosis, obesity, overweight, appetite, anti-obesity, weight loss, bodyweight, food intake, feed intake, metabolic syndrome, metabolic syndromes, metabolic syndrome X, insulin resistance syndrome, dysmetabolic syndrome X, reaven syndrome X, metabolic cardiovascular syndrome, cardiometabolic syndrome, cardiometabolic syndromes, Withania somnifera , winter cherry, Indian ginseng, ashwagandha, withanias, withaferins, withanolides and withanosides