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By generating adenosine triphosphate (ATP) through oxidative phosphorylation, mitochondria provide energy for multiple cell activities and determine the cell fate like activation and differentiation ( This review aimed to summarize the current research advances on physiological and pathological roles of mitochondria., Mitophagy defects of antioxidant defense and mitochondrial dysfunction contributing to SLE immunopathogenesis were systematically reviewed

It has not received a marketing authorisation from the MHRA or a positive opinion from the EMA

The review also concludes that although early studies are promising, most have involved small groups of patients, different study designs, and short follow-up periods

The immunophenotypic profile of cytokeratin+/HMB45+/S100- is an interesting combination