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HIF signaling changes the extracellular matrix, regulates the tumor immune response, increases angiogenesis, and affects the tumor microenvironment, altering the metabolism of tumor and stromal cells and increasing tumor invasiveness and metastasis (131)

Clinical potential Patients with gastric ulcers often experience recurrent conditions due to abnormal gastric acid secretion or impaired mucosal defense mechanisms

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The following events take place during this phase: normal variation, shedding, regeneration, duration, dormancy, and factors affecting telogen