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Those who had taken melatonin for at least one year were classified in the "melatonin group," while individuals with no record of melatonin use were placed in the "non-melatonin group." "Melatonin supplements may not be as harmless as commonly assumed

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This was evidenced by an inverse correlation between SOD activity and superoxide levels (r = 0.9447) and a positive correlation between SOD and catalase activity in the VC + VE group (r = 0.8586)