Key Takeaways Fried and high-fat foods are the #1 cause of severe GI symptoms on GLP-1 medications limit these strictly Sugary foods and refined carbs undermine weight loss goals and can trigger blood sugar swings Alcohol carries multiple risks including hypoglycaemia and delayed intoxication safest to avoid entirely during active weight loss Reflux-triggering foods (spicy, citrus, tomato, chocolate, peppermint, coffee) may become problematic even if they were fine before Ultra-processed foods waste limited appetite on empty calories every meal should be nutrient-dense Increase fibre gradually to prevent constipation abrupt increases cause bloating and pain Coffee is okay in moderation but only with food, never on an empty stomach Individual triggers vary keep a food diary for the first 4 weeks to identify your personal problem foods All GLP-1 medications (Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus, Foundayo) share essentially the same food-avoidance list References Cleveland Clinic

James LP, Simpson PM, Capperelli E, Roberts DW, Hinson JA, Davern TJ, Lee WM: Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure
The study was led by Bradley Peterson, MD, of the Keck School of Medicine of the University of Southern California and co-authors included Corinna Koebnick, PhD, and Brian S
Most cases of constipation are mild to moderate and tend to improve as the body adjusts to the medication, typically within the first few weeks to months of treatment