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doi: 10.1016/S1016-8478(23)13093-7

In conclusion, GLP-1RAs promoted macrophage polarization towards the M2 type, improving the inflammatory microenvironment of the synovium, maintaining synovial homeostasis, and inhibiting the progression of RA

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HT: Henning Langer #GLP1 #Weightloss #olderadults Thank you for sharing, I believe when Retatrutide enter the market with its triple hormone activity would lower the muscle mass loss compared to older GLPs The distinction between weight-loss-driven lean mass reduction and tissue-specific GLP-1 effects is critical, especially in older adults where baseline sarcopenia prevalence is already high