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Variants in the GLP1R gene (such as rs6923761) and the GIPR pathway influence how effectively your receptors respond to the medication, meaning some people see dramatic appetite suppression in week 2 while others require until week 6

Weight loss results were consistently superior to placebo and to comparator medications including semaglutide

"I've run into those people a couple of months later, and they've lost heaps of weight, and they very shyly said, 'I've been using a weight-loss drug,'" she related

While some people might notice subtle changes within a few weeks, the most significant improvements from KLOW therapy typically appear after about 8 to 12 weeks of consistent use