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Clone with a Q45R substitution showed the best activity and was named G2 (Supplementary Fig

Some research suggests that AHK-Cu could be more potent in activating specific pathways related to collagen production, potentially leading to more pronounced effects on skin firmness and elasticity

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Dermatologists could respond by advocating use of barrier methods as barrier methods are not reliant on the GI system and therefore are less likely impacted by GLP-1 agonists