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doi: 10.1093/ajcn/nqaa177 252 SekharR

Some prescribers recommend periodic breaks or dose reductions after achieving weight loss goals, while others advocate for continuous therapy to prevent weight regain

Studies on mechanisms of anti-atherogenic activity of HDL, mainly reverse cholesterol transport, have also led to the discovery of dysfunctional HDL, developed in inflammatory and/or oxidative stress conditions (as well as a result of glycation and other processes), with limited or nullified anti-atherosclerotic activity, or even with pro-atherosclerotic properties [41]

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