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NEJM article

Potential Side Effects and Safety Considerations Like any prescription medication, phentermine comes with potential side effects

Apart from DNA and RNA synthesis, augmented GTP nucleotide pools have been associated with promoting metastasis across several cancer types via the activation of RHO-family GTPases, which are involved in extracellular matrix degradation, basement membrane invasion, and cell migration [85, 86]

Intracellular and extracellular alteration of amino acid metabolism in the tumor microenvironment can influence cancer growth, progression, and metastasis