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Then we used Tunel fluorescence staining to detect the apoptosis signal in islet cells and immunofluorescence staining for the value-added related antigen Ki67 (Figures 2E, F)

doi: 10.3389/fphar.2023.1231320 Received 05 June 2023 Accepted 09 November 2023 Published 17 November 2023 Volume 14 - 2023 Edited by Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by Xiaotong Mao, Second Military Medical University, China Qiuxia Min, The First Peoples Hospital of Yunnan Province, China Kennedy Otwombe, University of the Witwatersrand, South Africa Updates Copyright 2023 Zhang, Mao, Liu, Hu, Lin, Ran, Li and Hu

Days 4-7: Symptoms usually peak around day 4-5, then begin to subside as your elimination pathways adapt to the increased workload