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ALS neuropathology is characterized by neuronal lesions located in the brain motor cortex for the upper motor neurons, the brain stem, and spinal cord for the lower motor neurons (Del Tredici and Braak, 2022)

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First described by Novo Nordisk researchers, ipamorelin is notable for its selectivity in stimulating growth hormone release without significantly affecting other pituitary hormones such as ACTH, prolactin, FSH, LH, or TSH in preclinical models

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