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The immunohistochemical analysis procedure was the same as that used in our previous study (16), in which we examined GLP-1R expression in PNETs and found no significant associations between the receptor expression status and several clinicopathological characteristics

The other differentiating factor is weight loss, as people with type 2 diabetes tend to gain weight and GLP-1 products promote weight loss

342,343,344 The formation of the NLRP3 inflammasome involves the recruitment of the adaptor protein ASC, which is then followed by the recruitment of caspase-1

Consumption of grapefruit, tangelo or Seville orange (or products containing grapefruit, tangelo or Seville orange) in the 10 days before the first administration of study drug and throughout the study