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(3) outcomes: Primary outcomes included CV death, major adverse cardiovascular events (MACE, a composite of CV death, nonfatal myocardial infarction (MI), or nonfatal stroke), expanded MACE [MACE components plus coronary revascularization, hospitalization for unstable angina or heart failure (HF)], nonfatal MI, nonfatal stroke, and hospitalization for HF

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Step Therapy / Alternative Required What it looks like: "Must try X first," "step edit." What to do: MASH now has another FDA-approved treatment option resmetirom (Rezdiffra), approved in March 2024 for noncirrhotic MASH with F2 to F3 fibrosis