Microneedling SkinPen Microneedling creates tiny micro-channels in the skin, triggering your bodys natural healing response to boost collagen and elastin, minimize imperfections, and restore a radiant, youthful glow
The most studied mechanisms include: upregulation of growth hormone receptors in fibroblasts (increasing sensitivity to healing signals), activation of the FAK-paxillin pathway (promoting cell adhesion and migration), modulation of the nitric oxide system through Src-Caveolin-1-eNOS phosphorylation (enhancing vascular function), and dual activation of the Egr-1/NAB2 gene loop (promoting organized, non-chaotic blood vessel growth)
The amount you receive varies based on the ingredients included
Rampon, C., Volovitch, M., Joliot, A