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As a reminder, SELECT enrolled 17,604 adults who were 45 years or older, overweight or obese, without diabetes and had a diagnosis of cardiovascular disease, including prior myocardial infarction, stroke, and/or peripheral artery disease

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There are certain treatments, minoxidil, steroids, that have sometimes been used in this situation, but they would only apply not so much as a preventive measure, but rather, kind of a treatment on the tail end, unfortunately, after it's already developed

Increasing sirtuins via increasing NAD levels promotes health and may help prevent diseases of aging, including cognitive decline, metabolic disease, cancer, and frailty