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Supplementation also becomes necessary because certain conditions, such as exposure to chemotherapy, radiation, heavy metals, etc., require a strong antioxidant to help protect the body and rid it of these oxidative stress markers

We draw attention to various factors that may perturb enterocytic balance between the thiamine influx from the lumen and systemic delivery to other tissues, providing insights into the molecular mechanisms of local thiamine insufficiency in gastrointestinal system

Laboratory tests have revealed that extracellular GMFB can decrease the number of RPECs and their cellcell connections and increase ACSL4 expression (35)

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