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As IL-1 has known effects on hypothalamic biogenic amines, the main source of corticotropin-releasing factor (CRF), it can regulate on pituitary ACTH and promote the production and release of cortisol (80), which may be the underlying mechanism of the HPA axis activation by IL-1

Experts suggest a quick "rebound" effect in appetite and metabolism after stopping the drug, compounded by the stress of pregnancy

Monthly costs for injectable GLP1 drugs can run hundreds (or even thousands) of dollars without insurance, putting them out of reach for many people

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