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We intend to specifically investigate the redox control of GSAAT, analyze the redox-dependent shifts in the thiol-disulphide state of GSAAT, and identify the redox-dependent cysteines responsible for changes in the structure, enzymatic activity and stability of the protein

ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)

Many are seeking faster healing of tendon, ligament, cartilage or muscle damage, said Frank, who is also a professor of orthopedics at the University of Colorado Anschutz School of Medicine

These factors can affect occurrence of nonproliferative as well as proliferative liver lesions in rodents