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Increased Sensitivity Some users report enhanced sensitivity and physical response during intimate moments

Moreover, the overexpression of O-GlcNAcase (OGA), which removes O-GlcNAc from proteins, significantly improved whole-body glucose tolerance and insulin sensitivity in db/db mice, and O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbamate (PUGNAc) (an OGA inhibitor) suppressed insulin-mediated glucose uptake in adipocytes [70,71]

As with any active, patch testing on a small area before full-face use is prudent, and anyone with very reactive skin or a known copper sensitivity should be cautious

If the reaction starts shortly after introducing a new product and gradually improves, its probably purging