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Phase 3 trials are currently ongoing (see ClinicalTrials.gov for the retatrutide Phase 3 programme), and these larger studies will provide more robust data on the long-term safety and tolerability of retatrutide across more diverse populations

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These studies highlight the healing efficacy of ADSC-EVs on chronic limb ischemia while revealing their clinical potential for angiogenic therapy

1 Introduction Melanoma is one of the most aggressive cancers due to its high metastatic potential and mortality rate (Greco and Cinquegrani, 2016), many of which exhibit antibacterial, antiviral, anti-inflammatory and anticancer activity (Molinski et al., 2009