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Clinical studies have confirmed that hyperhomocysteinemia is not only an independent risk factor for the development of cardiovascular and cerebrovascular diseases, such as atherosclerosis, acute myocardial infarction, stroke, coronary artery lesions, and peripheral vascular disease, but also increases the risk of neurodegenerative disorders and tumors, and impairs the efficacy of antifolate drugs

doi: 10.1016/j.cmet.2018.03.001 21 ZhaoXWangMWenZLuZCuiLFuCet al

[DOI] [PubMed] [Google Scholar] 4.Ludvik B, Giorgino F, Jdar E, Frias JP, Fernndez Land L, Brown K, et al

In addition to its impressive antioxidant properties, its also said to serve as a physiological buffer that plays a key role in proper enzyme and calcium regulation