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In addition, thymosin beta-4s biological activities, including promotion of cell migration, angiogenesis and reduced inflammation, have been observed in human clinical trials for dermal repair, showing potential for improved recovery and reduced inflammatory responses in injured tissues

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Furthermore, as a specific cargo receptor involved in autophagy, NCOA4 bound ferritin and delivered it to lysosomes for degradation, resulting in the release of free iron and an increase in the level of the LIP in cells (Fig