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The expiration date marks the point at which the manufacturer (or compounding pharmacy) can no longer guarantee the medication contains the labeled dose and remains free from harmful bacterial growth

Researchers sought to investigate the efficacy of L-citrulline and/or GSH on markers indicative of NO synthesis and found that daily oral supplementation with 200mg of Setria Glutathione and 2g of L-citrulline enhanced levels of nitric oxide, concluding that Setria Glutathione not only enhanced blood levels of NO, but may sustain levels by preventing its oxidative reaction when ingested in combination with L-citrulline

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An imbalance of the gut microbiota can lead to immune activation and inflammation, particularly through an increase in pro-inflammatory lipopolysaccharides (LPS), which results in increased production of inflammatory cytokines, such as TNF-, IL-1, and IL-6 (218)