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Specific loss of GIPR signaling in GABAergic neurons enhances GLP-1R agonist-induced body weight loss

GLP-1s, a class of drugs used to treat type 2 diabetes, obesity, cardiovascular disease, and other conditions, have exploded in popularity in recent years due to their demonstrated effectiveness, but are often not covered by insurance, particularly for the treatment of obesity

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The medication functions by targeting three separate receptors that regulate appetite, blood sugar, and insulin utilization