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We also report that 13% of patients with type 1 diabetes in our registry use adjuvant glucose-lowering therapy in addition to insulin, significantly higher than the 5.4% reported from the T1D Exchange Registry in the US [18]

Cell 41 , 325334 (1985)

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This pattern supports the interpretation of decreased C2 levels as a potential trait marker indexing an underlying vulnerability for the development of depression, in line with previous genetic analyses [32]