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Sucha M, Benediktova S, Tichanek F, Jedlicka J, Kapl S, Jelinkova D, et al

Although, Ihh is a critical modulator that promotes PTHrP expression in the growth plate, our observations on the decreased Ihh expression in the Cart IGF-IR / and TamCar IGF-IR / growth plates, however, support an Ihh-independent negative regulation of PTHrP expression and, perhaps, a direct effect on Ihh expression by IGF-IR signaling (41) (Figure 1)

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All tumor sizes complied with the guidelines of the Laboratory Animal Center at the National Taiwan University College of Medicine (Taiwan), under the approved IACUC protocol (No