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Since patients who developed EGFR mutant lung adenocarcinomas with acquired resistance to EGFR inhibitor drugs (gefitinib or erlotinib) exhibit increased copy numbers of MET, c-Met-HGF inhibitors are used for lung cancer treatment alone or in combination with other drugs [148]

Several diseases common in the very preterm infants, including bronchopulmonary dysplasia (BPD), susceptibility to infection, necrotizing enterocolitis (NEC), intraventricular hemorrhage (IVH), and retinopathy of prematurity (ROP), which largely contribute to the higher neonatal mortality of preterm infants, have been shown to be associated with free radicals responsible for increased oxidant stress

High reaction rates and contributions of glucuronidation and oxidation were observed in the pericentral region, while sulfation was promoted in the periportal region

The name BPC comes from Body Protection Compound, a term used in research literature connected to gastric peptide biology and cytoprotective pathway studies