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Si bien el ambiente hormonal desempea un rol indiscutible en este proceso, el balance calrico negativo es el que inclina la balanza hacia la prdida de grasa

[PubMed: 16904799] (Evaluation of the safety of oral ALA in rats who exhibited no evidence of toxicity except at the highest doses tested [121 mg/kg], which was associated with minor ALT elevations in males and slight changes in liver histology including small droplet fat in periportal regions, but without frank hepatocyte necrosis or inflammation)

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