This isnt just a minor concern
The synthetic peptide was synthesized starting in the 1990s
(Cheatham et al., 2023) Side effects of anti-obesity medication Short-term side effects of GLP-1 medications include, but are not limited to: Stomach issues (nausea, vomiting, abdominal pain, or distention) Gastrointestinal issues (diarrhea, constipation, or flatulence) Fatigue Dizziness Runny nose, Sore throat Headache Vision changes Allergic reactions Increased heart rate Depression Suicidal thoughts Though every individual responds to drug therapies differently, in a review of the evidence, the NASM evidence-based review on GLP-1 medications points out that the most common side effects are nausea, constipation, vomiting and diarrhea though a significant proportion of users did not report adverse effects (Cheatham et al., 2023) Do medications for obesity affect body composition
For those with IBS-C, careful management and personalization are key to avoiding increased discomfort