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In a Phase 2 trial, patients with early Parkinsons disease taking an older GLP-1 diabetes drug called lixisenatide experienced no worsening of motor symptoms over a year, in contrast to patients on placebo who did, according to the study, published Wednesday in the New England Journal of Medicine

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In this study, we investigate the potential of targeting Pf GR with conventional antimalarials and dual drugs combining aminoquinoline derivatives with GR inhibitors, which reveal promising interactions between Pf GR and studied drugs