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Can injecting semaglutide early cause low blood sugar or other dangerous side effects

Canonico, M., Oger, E., Plu-Bureau, G., Conard, J., Meyer, G., Lvesque, H., Trillot, N., Barrellier, M

In the STEP 2 study, there were greater proportions of females in the semaglutide group versus placebo (55% versus 47%) and patients who had never smoked (61% in the semaglutide group versus 55% in the placebo group)

Thus, direct GLP-1R signaling in SPNs might have clinical relevance as it may account for increased heart rate, a common side effect of GLP-1R agonist medications 21