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Obesity-related metabolic disturbances, including metabolic syndrome, insulin resistance, and chronic low-grade inflammation, further contribute to OSAS pathogenesis

39 OberdoerfferP.MichanS.McVayM.MostoslavskyR.VannJ.ParkS.-K.et al (2008)

- , 10-15%

:contentReference[oaicite:15] Here is a simple rule many clinicians use: If you feel stable and side effects are mild, you may be ready for the next step