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Materials and methods Experimental design and induction of the PCOS rat model The ethics committee of Shiraz University of Medical Sciences approved the study protocol (IR.SUMS.AEC.1403.010)

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Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management (weight loss and weight maintenance) in adult patients with an initial body mass index (BMI) of 30 kg/m 2 or greater (obesity) or 27 kg/m 2 or greater (excess weight) in the presence of at least one weight related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

Saxenda (liraglutide 3.0 mg) is a GLP-1 receptor agonist licensed for weight management in adults with obesity and certain adolescents