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This indicates the efficacy of using MET inhibitors alongside ICIs in treating tumors where MET is dysregulated and PD-L1 expression is elevated

New agents for targeting calcium signaling include calcium-ATPase inhibitors, voltage-gated calcium channel inhibitors, transient receptor potential (TRP) channel inhibitors, and Orai inhibitors, although most of these agents are still in the early stages of studies

Many of these molecules also display clinically relevant bioactivities, including anti-inflammatory, anticancer, cardioprotective, and neuroprotective effects, positioning them as promising agents for therapeutic applications and functional food products (Shah et al., 2018

Delayed gastric emptying means the drug sits in stomach acid longer before reaching the intestines where it gets absorbed